Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells

Chronic lymphocytic leukemia (CLL) is an incurable progressive disease for which new therapies are required. Therapy with monoclonal antibodies (mAbs) has improved the outcome of patients with CLL, making further investigation of novel antibodies directed against alternative and specific targets on...

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Main Authors: Hertlein, Erin, Triantafillou, Georgia, Sass, Ellen J., Hessler, Joshua D., Zhang, Xiaoli, Jarjoura, David, Lucas, David M., Muthusamy, Natarajan, Goldenberg, David M., Lee, Robert J., Byrd, John C.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Lymphoid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953888/
https://ncbi.nlm.nih.gov/pubmed/20574049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-253203
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