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Combining milatuzumab (anti-CD74 humanized antibody) with bortezomib, doxorubicin, or dexamethasone improves responses in multiple myeloma cell lines

PURPOSE: The humanized anti-CD74 monoclonal antibody, milatuzumab, is in clinical evaluation for the therapy of multiple myeloma (MM). The ability of milatuzumab to increase the efficacy of bortezomib, doxorubicin, and dexamethasone was examined in three human CD74+ MM cell lines, CAG, KMS11, KMS12-...

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Bibliografiske detaljer
Main Authors: Stein, Rhona, Smith, Mitchell R., Chen, Susan, Zalath, Maria, Goldenberg, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681251/
https://ncbi.nlm.nih.gov/pubmed/19351768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1953
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