Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

BACKGROUND: Dynamic changes to the epigenome play a critical role in establishing and maintaining cellular phenotype during differentiation, but little is known about the normal methylomic differences that occur between functionally distinct areas of the brain. We characterized intra- and inter-indi...

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Autores principales: Davies, Matthew N, Volta, Manuela, Pidsley, Ruth, Lunnon, Katie, Dixit, Abhishek, Lovestone, Simon, Coarfa, Cristian, Harris, R Alan, Milosavljevic, Aleksandar, Troakes, Claire, Al-Sarraj, Safa, Dobson, Richard, Schalkwyk, Leonard C, Mill, Jonathan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446315/
https://ncbi.nlm.nih.gov/pubmed/22703893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-6-r43
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