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Secondary structure specificity of the nuclease activity of the 1,10-phenanthroline-copper complex.
The artificial DNase activity of the 1,10-phenanthroline-cuprous ion complex [(OP)2Cu+] and H2O2 cleaves the A, B, and Z forms of DNA at different rates. The B structure, formed by most DNAs including poly(dA-dT) and poly(dA) X poly(dT), is the most susceptible to cleavage. It is completely degraded...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6320169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.1.3 |
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