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NFAT1 supports tumor-induced anergy of CD4+ T cells

Cancer cells express antigens that elicit T cell-mediated responses, but these responses are limited during malignant progression by the development of immunosuppressive mechanisms in the tumor microenvironment that drive immune escape. T cell hypo-responsiveness can be caused by clonal anergy or ad...

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Detalhes bibliográficos
Main Authors: Abe, Brian T, Shin, Daniel S, Mocholi, Enric, Macian, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445721/
https://ncbi.nlm.nih.gov/pubmed/22865456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3775
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