Regulatory T cells suppress CD4(+) T cells through NFAT-dependent transcriptional mechanisms

Regulatory T cells (Tregs) control autoreactive T cells by inhibiting activation-induced proliferation and cytokine expression. The molecular mechanisms responsible for the inactivation of effector T cells by Tregs remain yet to be fully characterized. We report that T-helper cells stimulated in the...

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Autori principali: Shin, Daniel S, Jordan, Ayana, Basu, Samik, Thomas, Rajan M, Bandyopadhyay, Sanmay, de Zoeten, Edwin F, Wells, Andrew D, Macian, Fernando
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198043/
https://ncbi.nlm.nih.gov/pubmed/25074018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201338233
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