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The Transcription Factor NFAT1 Participates in the Induction of CD4(+) T Cell Functional Exhaustion during Plasmodium yoelii Infection
Repeated stimulation of T cells that occurs in the context of chronic infection results in progressively reduced responsiveness of T cells to pathogen-derived antigens. This phenotype, known as T cell exhaustion, occurs during chronic infections caused by a variety of pathogens, from persistent viru...
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| Udgivet i: | Infect Immun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563568/ https://ncbi.nlm.nih.gov/pubmed/28630062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00364-17 |
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