MicroRNA-21 Modulates the Levels of Reactive Oxygen Species Levels by Targeting SOD3 and TNFα

MicroRNA-21 (miR-21) is an oncomir overexpressed in most human tumors where it promotes malignant growth and progression by acting on multiple targets. Here we broaden the impact of miR-21 in cancer by demonstrating that it regulates formation of reactive oxygen species (ROS) that promote tumorigene...

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Hlavní autoři: Zhang, Xiangming, Ng, Wooi-Loon, Wang, Ping, Tian, LinLin, Werner, Erica, Wang, Huichen, Doetsch, Paul, Wang, Ya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445705/
https://ncbi.nlm.nih.gov/pubmed/22836756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0639
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