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Reactive Oxygen Species in TNFα-Induced Signaling and Cell Death

TNFα is a pleotropic cytokine that initiates many downstream signaling pathways, including NF-κB activation, MAP kinase activation and the induction of both apoptosis and necrosis. TNFα has shown to lead to reactive oxygen species generation through activation of NADPH oxidase, through mitochondrial...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Morgan, Michael J., Liu, Zheng-gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608586/
https://ncbi.nlm.nih.gov/pubmed/20652490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-010-0105-0
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