Opposite Roles for p38MAPK-Driven Responses and Reactive Oxygen Species in the Persistence and Resolution of Radiation-Induced Genomic Instability

We report the functional and temporal relationship between cellular phenotypes such as oxidative stress, p38MAPK-dependent responses and genomic instability persisting in the progeny of cells exposed to sparsely ionizing low-Linear Energy Transfer (LET) radiation such as X-rays or high-charge and hi...

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Bibliographische Detailangaben
Hauptverfasser: Werner, Erica, Wang, Huichen, Doetsch, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182705/
https://ncbi.nlm.nih.gov/pubmed/25271419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108234
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