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MicroRNA-21 Modulates the Levels of Reactive Oxygen Species Levels by Targeting SOD3 and TNFα

MicroRNA-21 (miR-21) is an oncomir overexpressed in most human tumors where it promotes malignant growth and progression by acting on multiple targets. Here we broaden the impact of miR-21 in cancer by demonstrating that it regulates formation of reactive oxygen species (ROS) that promote tumorigene...

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Bibliografiske detaljer
Main Authors: Zhang, Xiangming, Ng, Wooi-Loon, Wang, Ping, Tian, LinLin, Werner, Erica, Wang, Huichen, Doetsch, Paul, Wang, Ya
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445705/
https://ncbi.nlm.nih.gov/pubmed/22836756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0639
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