A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101

PURPOSE: Sensory peripheral neuropathy is a common and sometimes debilitating toxicity associated with paclitaxel therapy. This study aims to identify genetic risk factors for development of this toxicity. EXPERIMENTAL DESIGN: A prospective pharmacogenetic analysis of primary breast cancer patients...

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Autores principales: Baldwin, R. Michael, Owzar, Kouros, Zembutsu, Hitoshi, Chhibber, Aparna, Kubo, Michiaki, Jiang, Chen, Watson, Dorothy, Eclov, Rachel J., Mefford, Joel, McLeod, Howard L., Friedman, Paula N., Hudis, Clifford A., Winer, Eric P., Jorgenson, Eric M., Witte, John S., Shulman, Lawrence N., Nakamura, Yusuke, Ratain, Mark J., Kroetz, Deanna L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445665/
https://ncbi.nlm.nih.gov/pubmed/22843789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1590
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