Polygenic Inheritance of Paclitaxel-Induced Sensory Peripheral Neuropathy Driven by Axon Outgrowth Gene Sets in CALGB 40101 (Alliance)

Peripheral neuropathy is a common dose-limiting toxicity for patients treated with paclitaxel. For most individuals there are no known risk factors that predispose patients to the adverse event, and pathogenesis for paclitaxel-induced peripheral neuropathy is unknown. Determining whether there is a...

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Autori principali: Chhibber, Aparna, Mefford, Joel, Stahl, Eli A., Pendergrass, Sarah A., Baldwin, R. Michael, Owzar, Kouros, Li, Megan, Winer, Eric P., Hudis, Clifford A., Zembutsu, Hitoshi, Kubo, Michiaki, Nakamura, Yusuke, McLeod, Howard L., Ratain, Mark J., Shulman, Lawrence N., Ritchie, Marylyn D., Plenge, Robert M., Witte, John S., Kroetz, Deanna L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111770/
https://ncbi.nlm.nih.gov/pubmed/24513692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.2
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