X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma

Scleroderma (SSc) is a rare connective tissue disease characterized by fibrosis, microvasculopathy and autoimmune features. The role of genetics is limited in SSc, as suggested by similar concordance rates in monozygotic and dizygotic twin pairs, while environmental factors may act through epigeneti...

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Autors principals: Selmi, C, Feghali-Bostwick, C A, Lleo, A, Lombardi, S A, De Santis, M, Cavaciocchi, F, Zammataro, L, Mitchell, M M, LaSalle, J M, Medsger Jr, T, Gershwin, M E
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445002/
https://ncbi.nlm.nih.gov/pubmed/22861365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04621.x
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