Genome-Wide Analysis of DNA Methylation, Copy Number Variation, and Gene Expression in Monozygotic Twins Discordant for Primary Biliary Cirrhosis

Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA and mRNA from peripheral blood cells of female MZ t...

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Detalhes bibliográficos
Main Authors: Selmi, Carlo, Cavaciocchi, Francesca, Lleo, Ana, Cheroni, Cristina, De Francesco, Raffaele, Lombardi, Simone A., De Santis, Maria, Meda, Francesca, Raimondo, Maria Gabriella, Crotti, Chiara, Folci, Marco, Zammataro, Luca, Mayo, Marlyn J., Bach, Nancy, Shimoda, Shinji, Gordon, Stuart C., Miozzo, Monica, Invernizzi, Pietro, Podda, Mauro, Scavelli, Rossana, Martin, Michelle R., Seldin, Michael F., LaSalle, Janine M., Gershwin, M. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975093/
https://ncbi.nlm.nih.gov/pubmed/24734033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00128
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