X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma

Scleroderma (SSc) is a rare connective tissue disease characterized by fibrosis, microvasculopathy and autoimmune features. The role of genetics is limited in SSc, as suggested by similar concordance rates in monozygotic and dizygotic twin pairs, while environmental factors may act through epigeneti...

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Detalhes bibliográficos
Main Authors: Selmi, C, Feghali-Bostwick, C A, Lleo, A, Lombardi, S A, De Santis, M, Cavaciocchi, F, Zammataro, L, Mitchell, M M, LaSalle, J M, Medsger Jr, T, Gershwin, M E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445002/
https://ncbi.nlm.nih.gov/pubmed/22861365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04621.x
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