X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma

Scleroderma (SSc) is a rare connective tissue disease characterized by fibrosis, microvasculopathy and autoimmune features. The role of genetics is limited in SSc, as suggested by similar concordance rates in monozygotic and dizygotic twin pairs, while environmental factors may act through epigeneti...

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Dettagli Bibliografici
Autori principali: Selmi, C, Feghali-Bostwick, C A, Lleo, A, Lombardi, S A, De Santis, M, Cavaciocchi, F, Zammataro, L, Mitchell, M M, LaSalle, J M, Medsger Jr, T, Gershwin, M E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445002/
https://ncbi.nlm.nih.gov/pubmed/22861365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04621.x
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