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SELECTIVE LOCAL DELIVERY OF RANK siRNA TO BONE PHAGOCYTES USING BONE AUGMENTATION BIOMATERIALS

Fracture healing and fracture fixation in the context of osteoporosis is extremely difficult. To inhibit osteoclast-induced bone resorption and associated implant loosening in this pathology, we describe a local delivery strategy to delivery RNA interfering technology to bone sites to target and dow...

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Detalhes bibliográficos
Main Authors: Wang, Yuwei, Tran, Kenny K., Shen, Hong, Grainger, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444628/
https://ncbi.nlm.nih.gov/pubmed/22951320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.07.039
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