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The Impact of Sphingomyelin Synthase 1 Deficiency on Sphingolipid Metabolism and Atherosclerosis in Mice

OBJECTIVE: Sphingomyelin synthase (SMS) catalyzes the conversion of ceramide to sphingomyelin (SM), and sits at the crossroads of sphingolipid biosynthesis. SMS has two isoforms: SMS1 and SMS2. Although they have the same SMS activity, they are different enzymes with distinguishable subcellular loca...

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Detalhes bibliográficos
Main Authors: Li, Zhiqiang, Fan, Yifan, Liu, Jing, Li, Yan, Quan, Chongmin, Bui, Hai H., Kuo, Ming-Shang, Park, Tae-Sik, Cao, Guoqing, Jiang, Xian-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444302/
https://ncbi.nlm.nih.gov/pubmed/22580896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.251538
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