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Macrophage Sphingomyelin Synthase 2 (SMS2) Deficiency Decreases Atherosclerosis in Mice
RATIONALE: Sphingomyelin synthase 2 (SMS2) contributes to de novo SM biosynthesis and plasma membrane SM levels. SMS2 deficiency in macrophages diminishes NFκB and MAP kinase activation induced by inflammatory stimuli. OBJECTIVE: The effects of SMS2 deficiency on the development of atherosclerosis a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746935/ https://ncbi.nlm.nih.gov/pubmed/19590047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.194613 |
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