Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-Infected Adults

BACKGROUND: The organic anion transporting polypeptides (OATP)/SLCO family represents an important class of hepatic drug uptake transporters that mediate the sodium independent transport of a diverse range of amphipathic organic compounds, including the protease inhibitors. The SLCO1B1 521T>C (rs...

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Detalhes bibliográficos
Main Authors: Schipani, Alessandro, Egan, Deirdre, Dickinson, Laura, Davies, Gerry, Boffito, Marta, Youle, Mike, Khoo, Saye H., Back, David J., Owen, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443796/
https://ncbi.nlm.nih.gov/pubmed/22477766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2095
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