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Influence of SLCO1B1 polymorphisms on lopinavir C (trough) in Serbian HIV/AIDS patients

AIMS: Lopinavir (LPV) is not a first‐line regimen. According to recent WHO data, LPV usage in low‐ and middle‐income countries accounted for approximately 52% of the adult and 23% of the paediatric protease inhibitor market in 2017. Since LPV is a substrate for the SLCO1B1 (OATP1B1) transporter, the...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Dragović, Gordana, Dimitrijević, Božana, Kušić, Jovana, Soldatović, Ivan, Jevtović, Djordje, Olagunju, Adeniyi, Owen, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319006/
https://ncbi.nlm.nih.gov/pubmed/32022294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14230
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