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DNA repair factor APLF is a histone chaperone

Poly(ADP-ribosyl)ation plays a major role in DNA repair, where it regulates chromatin relaxation as one of the critical events in the repair process. However, the molecular mechanism by which poly(ADP-ribose) modulates chromatin remains poorly understood. Here we identify the poly(ADP-ribose)-regula...

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Detalhes bibliográficos
Main Authors: Mehrotra, Pawan Vinod, Ahel, Dragana, Ryan, Daniel P., Weston, Ria, Wiechens, Nicola, Kraehenbuehl, Rolf, Owen-Hughes, Tom, Ahel, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443741/
https://ncbi.nlm.nih.gov/pubmed/21211722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.008
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