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Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts

Induction of pluripotency in differentiated cells through the exogenous expression of the transcription factors Oct4, Sox2, Klf4 and cellular Myc involves reprogramming at the epigenetic level. Histones and their metabolism governed by histone chaperones constitute an important regulator of epigenet...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Syed, Khaja Mohieddin, Joseph, Sunu, Mukherjee, Ananda, Majumder, Aditi, Teixeira, Jose M., Dutta, Debasree, Pillai, Madhavan Radhakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201018/
https://ncbi.nlm.nih.gov/pubmed/27875275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.194035
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