Enhanced expression of histone chaperone APLF associate with breast cancer

Abstract DNA damage-specific histone chaperone Aprataxin PNK-like factor (APLF) regulates mesenchymal-to-epithelial transition (MET) during cellular reprogramming. We investigated the role of APLF in epithelial-to-mesenchymal transition (EMT) linked to breast cancer invasiveness and metastasis. Here...

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Detalhes bibliográficos
Main Authors: Aditi Majumder, Khaja Moheiddin Syed, Ananda Mukherjee, Manendra Babu Lankadasari, Juberiya Mohammed Azeez, Sreeharshan Sreeja, Kuzhuvelil B. Harikumar, Madhavan Radhakrishna Pillai, Debasree Dutta
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-03-01
Colecção:Molecular Cancer
Assuntos:
Histone chaperone
APLF
Invasive breast cancer
EMT
Acesso em linha:http://link.springer.com/article/10.1186/s12943-018-0826-9
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