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Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts

Induction of pluripotency in differentiated cells through the exogenous expression of the transcription factors Oct4, Sox2, Klf4 and cellular Myc involves reprogramming at the epigenetic level. Histones and their metabolism governed by histone chaperones constitute an important regulator of epigenet...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Syed, Khaja Mohieddin, Joseph, Sunu, Mukherjee, Ananda, Majumder, Aditi, Teixeira, Jose M., Dutta, Debasree, Pillai, Madhavan Radhakrishna
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201018/
https://ncbi.nlm.nih.gov/pubmed/27875275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.194035
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