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DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface
Genome replication, transcription and repair require the assembly/disassembly of the nucleosome. Histone chaperones are regulators of this process by preventing formation of non-nucleosomal histone–DNA complexes. Aprataxin and polynucleotide kinase like factor (APLF) is a non-homologous end-joining...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101569/ https://ncbi.nlm.nih.gov/pubmed/29905837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky507 |
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