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The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding

BACKGROUND: The ribonuclease H (RNase H) domains of retroviral reverse transcriptases play an essential role in the replication cycle of retroviruses. During reverse transcription of the viral genomic RNA, an RNA/DNA hybrid is created whose RNA strand needs to be hydrolyzed by the RNase H to enable...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Leo, Berit, Schweimer, Kristian, Rösch, Paul, Hartl, Maximilian J, Wöhrl, Birgitta M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443672/
https://ncbi.nlm.nih.gov/pubmed/22962864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-73
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