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PKD Controls αvβ3 Integrin Recycling and Tumor Cell Invasive Migration Through its Substrate Rabaptin-5
Integrin recycling is critical for cell migration. Protein Kinase D (PKD) mediates signals from the platelet-derived growth factor-receptor (PDGF-R) to control αvβ3 integrin recycling. We now show that Rabaptin-5, a Rab5 effector in endosomal membrane fusion, is a PKD substrate. PKD phosphorylates R...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443396/ https://ncbi.nlm.nih.gov/pubmed/22975325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.08.008 |
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