Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments

Here we show that blocking the adhesive function of αvβ3 integrin with soluble RGD ligands, such as osteopontin or cilengitide, promoted association of Rab-coupling protein (RCP) with α5β1 integrin and drove RCP-dependent recycling of α5β1 to the plasma membrane and its mobilization to dynamic ruffl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Caswell, Patrick T., Chan, May, Lindsay, Andrew J., McCaffrey, Mary W., Boettiger, David, Norman, Jim C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2008
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2557049/
https://ncbi.nlm.nih.gov/pubmed/18838556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804140
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia