Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration

Inhibition of αvβ3 integrin or expression of oncogenic mutants of p53 promote invasive cell migration by enhancing endosomal recycling of α5β1 integrin under control of the Rab11 effector Rab-coupling protein (RCP). In this paper, we show that diacylglycerol kinase α (DGK-α), which phosphorylates di...

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Autori principali: Rainero, Elena, Caswell, Patrick T., Muller, Patricia A.J., Grindlay, Joan, McCaffrey, Mary W., Zhang, Qifeng, Wakelam, Michael J.O., Vousden, Karen H., Graziani, Andrea, Norman, Jim C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2012
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265946/
https://ncbi.nlm.nih.gov/pubmed/22270919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201109112
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