The Diacylglycerol Kinase α/Atypical PKC/β1 Integrin Pathway in SDF-1α Mammary Carcinoma Invasiveness

Diacylglycerol kinase α (DGKα), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix invasion. We previously demonstrated that in epithelial cells activation of DGKα activity promotes cytoskeletal remodeling and matrix invasion by recruiti...

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Hauptverfasser: Rainero, Elena, Cianflone, Cristina, Porporato, Paolo Ettore, Chianale, Federica, Malacarne, Valeria, Bettio, Valentina, Ruffo, Elisa, Ferrara, Michele, Benecchia, Fabio, Capello, Daniela, Paster, Wolfgang, Locatelli, Irene, Bertoni, Alessandra, Filigheddu, Nicoletta, Sinigaglia, Fabiola, Norman, Jim C., Baldanzi, Gianluca, Graziani, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041662/
https://ncbi.nlm.nih.gov/pubmed/24887021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097144
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