Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide

Standard tuberculosis (TB) treatment includes an initial regimen containing drugs that are both rapidly bactericidal (isoniazid) and sterilizing (rifampin and pyrazinamide), and ethambutol to help prevent the emergence of drug resistance. Antagonism between isoniazid and pyrazinamide has been demons...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Grosset, Jacques, Almeida, Deepak, Converse, Paul J., Tyagi, Sandeep, Li, Si-Yang, Ammerman, Nicole C., Pym, Alexander S., Wallengren, Kristina, Hafner, Richard, Lalloo, Umesh, Swindells, Susan, Bishai, William R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443175/
https://ncbi.nlm.nih.gov/pubmed/22927424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203636109
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