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CD3-mediated activation of tumor-reactive lymphocytes from patients with advanced cancer

Lymphocytes from blood or tumors of patients with advanced cancer did not proliferate and produced very low levels of tumor necrosis factor and IFN-γ when cultured with autologous tumor cells. Proliferation and lymphokine production dramatically increased in the presence of beads conjugated with mAb...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hellström, Ingegerd, Ledbetter, Jeffrey A., Scholler, Nathalie, Yang, Yi, Ye, Zhengmao, Goodman, Gary, Pullman, Janice, Hayden-Ledbetter, Martha, Hellström, Karl Erik
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021557498
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