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CD3-mediated activation of tumor-reactive lymphocytes from patients with advanced cancer

Lymphocytes from blood or tumors of patients with advanced cancer did not proliferate and produced very low levels of tumor necrosis factor and IFN-γ when cultured with autologous tumor cells. Proliferation and lymphokine production dramatically increased in the presence of beads conjugated with mAb...

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Sparad:
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Hellström, Ingegerd, Ledbetter, Jeffrey A., Scholler, Nathalie, Yang, Yi, Ye, Zhengmao, Goodman, Gary, Pullman, Janice, Hayden-Ledbetter, Martha, Hellström, Karl Erik
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2001
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021557498
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