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CD3-mediated activation of tumor-reactive lymphocytes from patients with advanced cancer

Lymphocytes from blood or tumors of patients with advanced cancer did not proliferate and produced very low levels of tumor necrosis factor and IFN-γ when cultured with autologous tumor cells. Proliferation and lymphokine production dramatically increased in the presence of beads conjugated with mAb...

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Wedi'i Gadw mewn:
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Hellström, Ingegerd, Ledbetter, Jeffrey A., Scholler, Nathalie, Yang, Yi, Ye, Zhengmao, Goodman, Gary, Pullman, Janice, Hayden-Ledbetter, Martha, Hellström, Karl Erik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2001
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021557498
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