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CD3-mediated activation of tumor-reactive lymphocytes from patients with advanced cancer

Lymphocytes from blood or tumors of patients with advanced cancer did not proliferate and produced very low levels of tumor necrosis factor and IFN-γ when cultured with autologous tumor cells. Proliferation and lymphokine production dramatically increased in the presence of beads conjugated with mAb...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hellström, Ingegerd, Ledbetter, Jeffrey A., Scholler, Nathalie, Yang, Yi, Ye, Zhengmao, Goodman, Gary, Pullman, Janice, Hayden-Ledbetter, Martha, Hellström, Karl Erik
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371607/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021557498
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