Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

Quantitative and qualitative defects in CD1-restricted natural killer T cells have been reported in several autoimmune-prone strains of mice, including the nonobese diabetic (NOD) mouse. These defects are believed to be associated with the emergence of spontaneous autoimmunity. Here we demonstrate t...

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Detalles Bibliográficos
Autores principales: Shi, Fu-Dong, Flodström, Malin, Balasa, Balaji, Kim, Soon Ha, Van Gunst, Kurt, Strominger, Jack L., Wilson, S. Brian, Sarvetnick, Nora
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC34429/
https://ncbi.nlm.nih.gov/pubmed/11390999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121169698
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