Increasing the chemical potential of the germ-line antibody repertoire.

To augment the chemical potential of the immunological repertoire, a metal ion-binding light chain has been introduced into the murine genome. Mice containing the transgene were subsequently immunized with a fluorescein conjugate. The transgenic light chain was found at a high frequency in the anti-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sarvetnick, N, Gurushanthaiah, D, Han, N, Prudent, J, Schultz, P, Lerner, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8483917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4008
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