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Increasing the chemical potential of the germ-line antibody repertoire.

To augment the chemical potential of the immunological repertoire, a metal ion-binding light chain has been introduced into the murine genome. Mice containing the transgene were subsequently immunized with a fluorescein conjugate. The transgenic light chain was found at a high frequency in the anti-...

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Detalhes bibliográficos
Main Authors: Sarvetnick, N, Gurushanthaiah, D, Han, N, Prudent, J, Schultz, P, Lerner, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46435/
https://ncbi.nlm.nih.gov/pubmed/8483917
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