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Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

IL-2 and IL-21 are two cytokines with great potential to affect autoimmune infiltration of nonlymphoid tissue, and are contained within the strongest non-MHC-linked locus for type 1 diabetes (T1D) susceptibility on the nonobese diabetic (NOD) mouse (Idd3). IL-21 is necessary for the development of d...

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Bibliografische gegevens
Hoofdauteurs: McGuire, Helen M., Vogelzang, Alexis, Hill, Natasha, Flodström-Tullberg, Malin, Sprent, Jonathan, King, Cecile
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780811/
https://ncbi.nlm.nih.gov/pubmed/19880748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903561106
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