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Crohn disease ATG16L1 polymorphism increases susceptibility to infection with Helicobacter pylori in humans

Autophagy plays key roles both in host defense against bacterial infection and in tumor biology. Helicobacter pylori (H. pylori) infection causes chronic gastritis and is the single most important risk factor for the development of gastric cancer in humans. Its vacuolating cytotoxin (VacA) promotes...

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Detalhes bibliográficos
Main Authors: Raju, Deepa, Hussey, Séamus, Jones, Nicola L.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442886/
https://ncbi.nlm.nih.gov/pubmed/22885761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21007
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