A systematic, family-wide investigation reveals that ~30% of mammalian PDZ domains engage in PDZ-PDZ interactions

PDZ domains are independently folded modules that typically mediate protein-protein interactions by binding to the C-termini of their target proteins. In a few instances, however, PDZ domains have been reported to dimerize with other PDZ domains. To investigate this noncanonical binding mode further...

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Detaylı Bibliyografya
Asıl Yazarlar: Chang, Bryan H., Gujral, Taranjit S., Karp, Ethan S., BuKhalid, Raghida, Grantcharova, Viara P., MacBeath, Gavin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442787/
https://ncbi.nlm.nih.gov/pubmed/21944753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.06.013
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