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Predicting PDZ domain–peptide interactions from primary sequences
PDZ domains constitute one of the largest families of interaction domains and function by binding the C termini of their target proteins1,2. Using Bayesian estimation, we constructed a three-dimensional extension of a position-specific scoring matrix that predicts to which peptides a PDZ domain will...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655215/ https://ncbi.nlm.nih.gov/pubmed/18711339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1489 |
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