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Predicting PDZ domain–peptide interactions from primary sequences

PDZ domains constitute one of the largest families of interaction domains and function by binding the C termini of their target proteins1,2. Using Bayesian estimation, we constructed a three-dimensional extension of a position-specific scoring matrix that predicts to which peptides a PDZ domain will...

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Bibliografski detalji
Glavni autori: Chen, Jiunn R, Chang, Bryan H, Allen, John E, Stiffler, Michael A, MacBeath, Gavin
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655215/
https://ncbi.nlm.nih.gov/pubmed/18711339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1489
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