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Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells
The eukaryotic genome is replicated according to a specific spatio-temporal programme. However, little is known about both its molecular control and biological significance. Here, we identify mouse Rif1 as a key player in the regulation of DNA replication timing. We show that Rif1 deficiency in prim...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442270/ https://ncbi.nlm.nih.gov/pubmed/22850673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.214 |
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