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Establishment of a replication fork barrier following induction of DNA binding in mammalian cells

Understanding the mechanisms that lead to replication fork blocks (RFB) and the means to bypass them is important given the threat that they represent for genome stability if inappropriately handled. Here, to study this issue in mammals, we use integrated arrays of the LacO and/or TetO as a tractabl...

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Detalhes bibliográficos
Main Authors: Beuzer, Paolo, Quivy, Jean-Pierre, Almouzni, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050166/
https://ncbi.nlm.nih.gov/pubmed/24675882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28627
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