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IgG-Fc glycoengineering in non-mammalian expression hosts

The remarkable success of therapeutic applications of immunoglobulin G (IgG) in form of monoclonal antibodies and pooled immunoglobulin G preparations has directed attention to this class of glycoproteins. It is commonly appreciated that oligosaccharides attached to the Fc-region play a critical rol...

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Bibliografiske detaljer
Main Authors: Loos, Andreas, Steinkellner, Herta
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442181/
https://ncbi.nlm.nih.gov/pubmed/22634260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.05.011
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