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Mnt Loss Triggers Myc Transcription Targets, Proliferation, Apoptosis, and Transformation
Myc oncoproteins are overexpressed in most cancers and are sufficient to accelerate cell proliferation and provoke transformation. However, in normal cells Myc also triggers apoptosis. All of the effects of Myc require its function as a transcription factor that dimerizes with Max. This complex indu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC344188/ https://ncbi.nlm.nih.gov/pubmed/14749372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1560-1569.2004 |
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