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Mnt Loss Triggers Myc Transcription Targets, Proliferation, Apoptosis, and Transformation
Myc oncoproteins are overexpressed in most cancers and are sufficient to accelerate cell proliferation and provoke transformation. However, in normal cells Myc also triggers apoptosis. All of the effects of Myc require its function as a transcription factor that dimerizes with Max. This complex indu...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC344188/ https://ncbi.nlm.nih.gov/pubmed/14749372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1560-1569.2004 |
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