c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

c-Myc promotes cell growth and transformation by ill-defined mechanisms. c-myc(−/−) mice die by embryonic day 10.5 (E10.5) with defects in growth and in cardiac and neural development. Here we report that the lethality of c-myc(−/−) embryos is also associated with profound defects in vasculogenesis...

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Bibliographic Details
Main Authors: Baudino, Troy A., McKay, Catriona, Pendeville-Samain, Helene, Nilsson, Jonas A., Maclean, Kirsteen H., White, Elsie L., Davis, Ann C., Ihle, James N., Cleveland, John L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC187450/
https://ncbi.nlm.nih.gov/pubmed/12368264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1024602
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