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c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
c-Myc promotes cell growth and transformation by ill-defined mechanisms. c-myc(−/−) mice die by embryonic day 10.5 (E10.5) with defects in growth and in cardiac and neural development. Here we report that the lethality of c-myc(−/−) embryos is also associated with profound defects in vasculogenesis...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187450/ https://ncbi.nlm.nih.gov/pubmed/12368264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1024602 |
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