c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression

c-Myc promotes cell growth and transformation by ill-defined mechanisms. c-myc(−/−) mice die by embryonic day 10.5 (E10.5) with defects in growth and in cardiac and neural development. Here we report that the lethality of c-myc(−/−) embryos is also associated with profound defects in vasculogenesis...

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Publicado en:	Genes Dev
Autores principales:	Baudino, Troy A., McKay, Catriona, Pendeville-Samain, Helene, Nilsson, Jonas A., Maclean, Kirsteen H., White, Elsie L., Davis, Ann C., Ihle, James N., Cleveland, John L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 2002
Materias:	Research Paper
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368264/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1024602
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